Boronic acid, B-1H-pyrrol-3-yl-
3-Pyrrolylboronic acid
CAS: 763120-55-4
Molecular Formula: C4H6BNO2
Boronic acid, B-1H-pyrrol-3-yl- - Names and Identifiers
Boronic acid, B-1H-pyrrol-3-yl- - Physico-chemical Properties
| Molecular Formula | C4H6BNO2 |
| Molar Mass | 110.91 |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD09751320 |
Boronic acid, B-1H-pyrrol-3-yl- - Introduction
3-Pyrrolylboronic acid is an organic compound with the chemical formula C4H6BNO2. It is a boronic acid derivative having a pyrrole ring structure. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 3-Pyrrolylboronic acid is a white to pale yellow solid.
-Solubility: 3-Pyrrolylboronic acid is soluble in many organic solvents or water.
Use:
-Coordination reagent: As a coordination reagent, it is often used in copper-catalyzed reactions, Suzuki-Miyaura coupling reactions and reductive denitrification reactions in organic synthesis.
-Synthesis intermediate: As an intermediate in organic synthesis, it can be used to synthesize compounds containing pyrrole groups, such as pyrrole-substituted aniline, pyrrole-substituted pyrrole, etc.
Preparation Method:
The preparation method of 3-Pyrrolylboronic acid is relatively simple, and the common preparation methods are as follows:
-addition method: pyrrole and boric acid are reacted to generate 3-Pyrrolylboronic acid.
-Deprotection reaction: 3-Pyrrolylboronic acid is obtained by removing the protecting group (such as ester or amide) of 3-Pyrrolylboronic acid.
Safety Information:
-Exposure of 3-Pyrrolylboronic acid should be avoided by inhalation, swallowing and skin contact.
-When using and handling this compound, you must wear appropriate personal protective equipment, such as laboratory gloves and protective glasses.
-This information only provides basic reference. When using and handling the compound, please refer to the safety data sheet of the substance and the safety operating procedures for related work.
Nature:
-Appearance: 3-Pyrrolylboronic acid is a white to pale yellow solid.
-Solubility: 3-Pyrrolylboronic acid is soluble in many organic solvents or water.
Use:
-Coordination reagent: As a coordination reagent, it is often used in copper-catalyzed reactions, Suzuki-Miyaura coupling reactions and reductive denitrification reactions in organic synthesis.
-Synthesis intermediate: As an intermediate in organic synthesis, it can be used to synthesize compounds containing pyrrole groups, such as pyrrole-substituted aniline, pyrrole-substituted pyrrole, etc.
Preparation Method:
The preparation method of 3-Pyrrolylboronic acid is relatively simple, and the common preparation methods are as follows:
-addition method: pyrrole and boric acid are reacted to generate 3-Pyrrolylboronic acid.
-Deprotection reaction: 3-Pyrrolylboronic acid is obtained by removing the protecting group (such as ester or amide) of 3-Pyrrolylboronic acid.
Safety Information:
-Exposure of 3-Pyrrolylboronic acid should be avoided by inhalation, swallowing and skin contact.
-When using and handling this compound, you must wear appropriate personal protective equipment, such as laboratory gloves and protective glasses.
-This information only provides basic reference. When using and handling the compound, please refer to the safety data sheet of the substance and the safety operating procedures for related work.
Last Update：2024-04-10 22:29:15
